Bears coach Lovie Smith said Roach would "probably not" participate in the final two practices of minicamp.
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"We'll take our time with Nick," Smith said. "He has a hamstring that's a little sore . . . he's gone through all the offseason work, so we know what Nick is about."
Pisa Tinoisamoa worked with the first team in place of Roach. The two are expected to battle for the job once training camp begins in late July.
Other players sitting out Saturday's workouts included tight end Brandon Manumaleuna, punter Brad Maynard and defensive tackle Marcus Harrison. Defensive tackle Tommie Harris missed the morning session, but participated in the afternoon practice.
Center Olin Kreutz, rehabbing from offseason surgery, ran on the side under the watchful eye of the Bears training staff.
Chicago Bears tight end Brandon Manumaleuna and receiver Earl Bennett are missing minicamp Friday after undergoing minor knee operationsIniesta out for a month