Edwards, who has had a rough start to the season with five drops for the 0-2 Browns, is dealing with an injured shoulder.
It's likely the Browns will be without guard Eric Steinbach, who strained his shoulder in last Sunday's loss to Pittsburgh, and linebacker Willie McGinest (hamstring). Both missed their third straight day of practice Friday.
Wide receiver Donte' Stallworth (quadriceps), who has yet to play in a game for Cleveland, missed practice again and is questionable.
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Bruised Bills QB Edwards out for Sunday’s game